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a prefix occurring originally in loanwords from Greek, where it was joined to verbs, deverbal forms, and other parts of speech. Among its functions in Greek, apo- has the spatial sense “away, off, apart” (apogee; apocope; apostasy; apostrophe); it occurs with deverbals that denote a response or defense (apodosis; apology) and is found on verbs having perfective force relative to a corresponding simple verb (apoplexy; aposiopesis). In modern scientific coinages in English and other languages, apo- marks things that are detached, separate, or derivative (apocarpous; apoenzyme).