(adj): of very great significance
(adj): highly significant or important especially bringing about or marking the beginning of a new development or era
(adj): sufficiently significant to affect the whole world
(adj): serving as or based on evidence
(adj): far-reaching and thoroughgoing in effect especially on the nature of something
(adj): fairly large or important in effect; influential
(adj): of outstanding significance
(adj): worthy of notice
(adj): tending to prove a particular proposition or to persuade you of the truth of an allegation
(adj): effective; producing a desired effect
(adj): of momentous or ominous significance
(adj): fairly large
(adj): vs. inconsiderable) -- (large or relatively large in number or amount or extent or degree
(adj): vs. nonsignificant) -- (too closely correlated to be attributed to chance and therefore indicating a systematic relation
(adj): prenominal), pregnant, significant -- (rich in significance or implication
(adj): vs. meaningless) -- (having a meaning or purpose
