(v): to exert much effort or energy
(v): cause annoyance in; disturb, especially by minor irritations
(v): give displeasure to
(v): to cause inconvenience or discomfort to
(v): have an effect upon
(v): intrude or enter uninvited
(v): enter uninvited
(v): make nervous or agitated
(v): cause to be agitated, excited, or roused
(v): make confused or perplexed or puzzled
(v): cause to feel embarrassment
(n): an angry disturbance
(n): activity that is a malfunction, intrusion, or interruption
(n): something or someone that causes trouble; a source of unhappiness
(n): a stimulus with undesirable consequences